免疫原
The antiserum was produced against synthesized peptide derived from human MRGX3. AA range:99-148
特异性
MRGX3 Polyclonal Antibody detects endogenous levels of MRGX3 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009],
功能
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
蛋白名称
Mas-related G-protein coupled receptor member X3
其他名称
MRGPRX3; MRGX3; SNSR1; SNSR2; Mas-related G-protein coupled receptor member X3; Sensory neuron-specific G-protein coupled receptor 1/2
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.