免疫原
The antiserum was produced against synthesized peptide derived from human LGR6. AA range:471-520
特异性
LGR6 Polyclonal Antibody detects endogenous levels of LGR6 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],
功能
function:Orphan receptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 16 LRR (leucine-rich) repeats.,
蛋白名称
Leucine-rich repeat-containing G-protein coupled receptor 6
其他名称
LGR6; Leucine-rich repeat-containing G-protein coupled receptor 6
Fields
>>Wnt signaling pathway
细胞定位
Cell membrane ; Multi-pass membrane protein .