免疫原
The antiserum was produced against synthesized peptide derived from human NK2R. AA range:301-350
特异性
NK-2R Polyclonal Antibody detects endogenous levels of NK-2R protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008],
功能
function:This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.,similarity:Belongs to the G-protein coupled receptor 1 family.,
蛋白名称
Substance-K receptor
其他名称
TACR2; NK2R; NKNAR; TAC2R; Substance-K receptor; SKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2
Fields
>>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Bone marrow,Lung,Stomach,Trachea,
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