免疫原
The antiserum was produced against synthesized peptide derived from human TOR1AIP1. AA range:431-480
特异性
LAP1B Polyclonal Antibody detects endogenous levels of LAP1B protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016],
功能
function:Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOR1AIP family.,subunit:Interacts with TOR1A.,
蛋白名称
Torsin-1A-interacting protein 1
其他名称
TOR1AIP1; Torsin-1A-interacting protein 1; Lamin-associated protein 1B; LAP1B
细胞定位
Nucleus inner membrane ; Single-pass membrane protein .
组织表达
Expressed in muscle, liver and kidney.
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