免疫原
Purified recombinant fragment of human KLHL1 expressed in E. Coli.
特异性
KLHL1 Monoclonal Antibody detects endogenous levels of KLHL1 protein.
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
背景(Background)
The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010],
功能
function:May play a role in organizing the actin cytoskeleton of the brain cells.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,tissue specificity:Highly expressed in brain.,
蛋白名称
Kelch-like protein 1
其他名称
KLHL1; KIAA1490; Kelch-like protein 1
细胞定位
Cytoplasm, cytoskeleton.
组织表达
Highly expressed in brain.