免疫原
Synthesized peptide derived from human Ankyrin B
特异性
This antibody detects endogenous levels of Ankyrin B at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.24% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
其他名称
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Fields
>>Proteoglycans in cancer
细胞定位
Cytoplasm, cytoskeleton . Membrane . Cytoplasm, myofibril, sarcomere, M line . Apical cell membrane . Cell membrane . Cell junction, synapse, postsynaptic cell membrane . Early endosome . Recycling endosome . Lysosome . Mitochondrion . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane, sarcolemma, T-tubule . Expressed at the apical membrane of airway lung epithelial cells (By similarity). Localized to the plasma membrane of the inner segments of photoreceptors in retina. Colocalizes with SPTBN1 in a distinct intracellular compartment of neonatal cardiomyocytes (PubMed:19007774). In skeletal muscle, localizes to neuromuscular junctions (By similarity). Localizes with puncta at mitochondria ends. Colocalizes and cotransports on motile vesicles with RABGAP1L (By similarity). .
组织表达
Present in plasma membrane of neurons as well as glial cells throughout the brain. Expressed in fetal brain and in temporal cortex of adult brain. Also expressed in the inner segments of rod photoreceptors in retina.