免疫原
Synthesized peptide derived from human STX3 AA range: 6-56
特异性
This antibody detects endogenous levels of STX3 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
功能
function:Potentially involved in docking of synaptic vesicles at presynaptic active zones.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,
基因名称（Gene Name）
STX3 STX3A
Fields
>>SNARE interactions in vesicular transport;>>Synaptic vesicle cycle
细胞定位
[Isoform A]: Apical cell membrane ; Single-pass type IV membrane protein . Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors. .; [Isoform 3]: Nucleus .
组织表达
[Isoform A]: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. ; [Isoform B]: Expressed only in the retina. ; [Isoform 3]: Ubiquitously expressed.
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