免疫原
Synthesized peptide derived from human ARMC9 AA range: 713-763
特异性
This antibody detects endogenous levels of ARMC9 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
similarity:Contains 1 LisH domain.,tissue specificity:Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis.,
基因名称(Gene Name)
ARMC9 KIAA1868
细胞定位
Cytoplasm, cytoskeleton, cilium basal body . Cell projection, cilium . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (By similarity). Localizes to the daughter centriole of the primary cilium in RPE1 cells (PubMed:28625504). .
组织表达
Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis.