免疫原
Synthesized peptide derived from human ARH40 AA range: 1261-1311
特异性
This antibody detects endogenous levels of ARH40 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014],
功能
function:May act as a guanine nucleotide exchange factor (GEF).,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,subcellular location:Concentrated in the perinuclear region.,tissue specificity:Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).,
基因名称(Gene Name)
ARHGEF40 SOLO
细胞定位
Cytoplasm . Concentrated in the perinuclear region.
组织表达
Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).