免疫原
Synthesized peptide derived from human GSTK1 AA range: 138-188
特异性
This antibody detects endogenous levels of GSTK1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],
功能
catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).,similarity:Belongs to the GST superfamily. Kappa family.,subunit:Homodimer.,tissue specificity:Ubiquitous.,
基因名称(Gene Name)
GSTK1 HDCMD47P
Fields
>>Glutathione metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Metabolic pathways;>>Peroxisome;>>Chemical carcinogenesis - DNA adducts