免疫原
Synthesized peptide derived from human MXRA8 AA range: 42-92
特异性
This antibody detects endogenous levels of MXRA8 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May play a role in the maturation and maintenance of blood-brain barrier.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Cytoplasm . Cell projection, cilium membrane . Nucleus . Primarily localizes to the cell membrane (PubMed:23386276). Detected in the cilium of primary chondrocytes (By similarity). Highly expressed at areas of cell-cell contact and may localize to tight junctions (By similarity). Also found in the nucleus where it is detected in the soluble (as opposed to chromatin-bound) fraction (PubMed:23386276). .
组织表达
Detected in endothelial cells in mammary tissue, in both large vessels (left internal mammary artery) and small capillaries (vasa vasorum of the adventitia).