免疫原
Synthesized peptide derived from human CLLU1 AA range: 23-73
特异性
This antibody detects endogenous levels of CLLU1 at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease. Methylation of certain genes, including this one, have been associated with CLL. This gene is protein-coding in humans and non-protein coding in other primates. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015],
功能
disease:High CLLU1 expression in patients with CLL is associated with poor clinical outcome.,miscellaneous:Tridimensional modeling predicts that it may interact with the IL-4 receptor.,tissue specificity:Specifically expressed in chronic lymphocytic leukemia (CLL) cells from patients without immunoglobulin heavy-chain hypermutations.,
细胞定位
Cytoplasm . Detected in the cytoplasm of chronic lymphocytic leukemia (CLL) cells.
组织表达
Specifically expressed in chronic lymphocytic leukemia (CLL) cells from patients without immunoglobulin heavy-chain hypermutations. Expression is detected in all CLL cells and levels are similar in patients before and after treatment.
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