免疫原
Synthesized peptide derived from human NOVA2 AA range: 274-324
特异性
This antibody detects endogenous levels of NOVA2 at Human
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
disease:Autoantigen in the paraneoplastic opsoclonus myoclonus ataxia (POMA), a paraneoplastic neurological syndrome/disorder (PNS/D) associated with breast cancer, fallopian cancer, and SCLCa and characterized primarily by loss of inhibitory control of motor neurons in the spinal cord and brainstem. Recognized by the IgG autoantibody ANNA-2 (also called anti-Ri).,domain:The third KH domain (KH3) recognizes specifically 5'-UCAY-3'.,function:May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.,similarity:Contains 3 KH domains.,subunit:Interacts with PTBP2.,tissue specificity:Brain. Expression restricted to astrocytes.,
基因名称(Gene Name)
NOVA2 ANOVA NOVA3
组织表达
Brain. Expression restricted to astrocytes.