免疫原
Synthesized peptide derived from human GKN1 AA range: 47-97
特异性
This antibody detects endogenous levels of GKN1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008],
功能
caution:It is uncertain whether Met-1 or Met-15 is the initiator.,function:Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.,similarity:Belongs to the gastrokine family.,similarity:Contains 1 BRICHOS domain.,tissue specificity:Expressed in stomach. No expression is detected in cancer tissue or gastric cancer cell lines.,
基因名称(Gene Name)
GKN1 AMP18 CA11 UNQ489/PRO1005
细胞定位
Secreted . Cytoplasmic granule . Golgi apparatus . Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. .
组织表达
Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines.