免疫原
Synthesized peptide derived from human SDC3 AA range: 131-181
特异性
This antibody detects endogenous levels of SDC3 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009],
功能
function:Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.,PTM:O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.,similarity:Belongs to the syndecan proteoglycan family.,tissue specificity:Expressed in the nervous system, the adrenal gland, and the spleen.,
基因名称(Gene Name)
SDC3 KIAA0468
Fields
>>Cell adhesion molecules
细胞定位
Cell membrane; Single-pass type I membrane protein.
组织表达
Expressed in the nervous system, the adrenal gland, and the spleen.