免疫原
Synthesized peptide derived from human FNDC1 AA range: 988-1038
特异性
This antibody detects endogenous levels of FNDC1 at Human/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
caution:It is uncertain whether Met-1 or Met-53 is the initiator.,function:May be an activator of G protein signaling.,induction:By TGF-beta present in the melanoma cell conditioned medium (MCCM).,similarity:Contains 5 fibronectin type-III domains.,tissue specificity:Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.,
基因名称(Gene Name)
FNDC1 FNDC2 KIAA1866 MEL4B3
组织表达
Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.