免疫原
Synthesized peptide derived from human PYDC1 AA range: 25-75
特异性
This antibody detects endogenous levels of PYDC1 at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1：50-200. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.,PTM:Phosphorylated.,similarity:Contains 1 DAPIN domain.,subunit:Interacts with PYCARD/ASC.,tissue specificity:Predominantly expressed in monocytes, macrophages and granulocytes.,
基因名称（Gene Name）
PYDC1 ASC2 ASCI POP1 PYC1
Fields
>>NOD-like receptor signaling pathway
细胞定位
Cytoplasm . Recruited to specks formed by PYCARD within the cytoplasm. .
组织表达
Predominantly expressed in monocytes, macrophages and granulocytes.
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