免疫原
Synthesized peptide derived from human PEF1 AA range: 109-159
特异性
This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010],
功能
similarity:Contains 5 EF-hand domains.,subcellular location:Membrane-associated in the presence of Ca(2+).,subunit:Heterodimer; heterodimerizes with PDCD6/ALG2. Dissociates from PDCD6/ALG2 in presence of Ca(2+).,
基因名称（Gene Name）
PEF1 ABP32 UNQ1845/PRO3573
细胞定位
Cytoplasm . Endoplasmic reticulum . Membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein . Membrane-associated in the presence of Ca(2+) (PubMed:11278427). Localizes to endoplasmic reticulum exit site (ERES) (By similarity). .
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