免疫原
Synthesized peptide derived from human PURA1 AA range: 14-64
特异性
This antibody detects endogenous levels of PURA1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the adenylosuccinate synthase family of proteins. The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP). Mutations in this gene may cause adolescent onset distal myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
功能
catalytic activity:GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP.,cofactor:Binds 1 magnesium ion per subunit.,function:Plays an important role in the de novo pathway of purine nucleotide biosynthesis.,pathway:Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.,similarity:Belongs to the adenylosuccinate synthetase family.,subunit:Homodimer.,tissue specificity:Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors.,
基因名称（Gene Name）
ADSSL1 ADSS1
Fields
>>Purine metabolism;>>Alanine, aspartate and glutamate metabolism;>>Metabolic pathways;>>Nucleotide metabolism;>>Biosynthesis of cofactors
组织表达
Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
