免疫原
Synthesized peptide derived from human RHBT2 AA range: 573-623
特异性
This antibody detects endogenous levels of RHBT2 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
功能
similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain.,
基因名称（Gene Name）
RHOBTB2 DBC2 KIAA0717
Fields
>>Ubiquitin mediated proteolysis
细胞定位
intracellular,cytosol,plasma membrane,
组织表达
Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain.
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