免疫原
Synthetic peptide from human protein at AA range: 141-190
特异性
The antibody detects endogenous IL-17D
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008],
功能
function:Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,tissue specificity:Expressed preferentially in adipose, skeletal muscle and CNS.,
基因名称(Gene Name)
IL17D IL27 UNQ3096/PRO21175
蛋白名称
Interleukin-17D (IL-17D) (Interleukin-27) (IL-27)
其他名称
Interleukin-17D (IL-17D;Interleukin-27;IL-27)
Fields
>>Cytokine-cytokine receptor interaction;>>C-type lectin receptor signaling pathway;>>JAK-STAT signaling pathway;>>IL-17 signaling pathway
组织表达
Expressed preferentially in adipose, skeletal muscle and CNS.