免疫原
Synthesized peptide derived from human Beta-defensin 1 AA range: 1-50
特异性
This antibody detects endogenous levels of human Beta-defensin 1
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景（Background）
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008],
功能
function:Has bactericidal activity.,mass spectrometry: PubMed:7628632,similarity:Belongs to the beta-defensin family.,tissue specificity:Plasma.,
基因名称（Gene Name）
DEFB1 BD1 HBD1
其他名称
Beta-defensin 1 (BD-1;hBD-1;Defensin, beta 1)
Fields
>>ABC transporters;>>Staphylococcus aureus infection
细胞定位
Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). .
组织表达
Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level).
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