免疫原
Synthesized peptide derived from human GNG4 AA range: 1-50
特异性
This antibody detects endogenous levels of human GNG4
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景(Background)
function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-2, but not with beta-3.,tissue specificity:Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.,
功能
function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-2, but not with beta-3.,tissue specificity:Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.,
基因名称(Gene Name)
GNG4 GNGT4
其他名称
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Fields
>>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
组织表达
Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.