免疫原
Synthesized peptide derived from human TIG1
特异性
This antibody detects endogenous levels of human TIG1
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
功能
induction:By tazarotene and by all the retinoic acid receptors tested.,similarity:Belongs to the protease inhibitor I47 (latexin) family.,
基因名称(Gene Name)
RARRES1 TIG1
其他名称
Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1;Tazarotene-induced gene 1 protein)
细胞定位
Membrane ; Single-pass type III membrane protein .