免疫原
Synthetic peptide from human protein at AA range: 1-50
特异性
The antibody detects endogenous PACAP
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
功能
function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
基因名称（Gene Name）
PACAP HSPC190
蛋白名称
Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)
其他名称
Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein;pERp1;Proapoptotic caspase adapter protein)
细胞定位
[Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
组织表达
Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat.
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