免疫原
Synthesized peptide derived from human Peripherin AA range: 85-135
特异性
This antibody detects endogenous levels of Peripherin at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.15% sodium azide.
稀释比例
IHC-p1:50-200 ,WB 1:1000-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
Peripherin(PRPH) Homo sapiens This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.
基因名称(Gene Name)
PRPH NEF4 PRPH1
其他名称
Peripherin (Neurofilament 4)
Fields
>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .
组织表达
Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.