免疫原
Synthesized peptide derived from human ABI2 AA range: 61-111
特异性
This antibody detects endogenous levels of human ABI2
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
基因名称(Gene Name)
ABI2 ARGBPIA
蛋白名称
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Fields
>>Regulation of actin cytoskeleton
细胞定位
Cytoplasm . Nucleus .; [Isoform 1]: Cell projection, lamellipodium . Cell projection, filopodium . Cytoplasm, cytoskeleton . Cell junction, adherens junction . Isoform 1 but not isoform 3 is localized to protruding lamellipodia and filopodia tips (PubMed:11516653, PubMed:15572692). Present at nascent adherens junctions, where it clusters adjacent to the tips of F-actin protrusions (PubMed:15572692). .
组织表达
Widely expressed. Abundant in testes, ovary, thymus, and colon, with lower but detectable levels in prostate, peripheral blood leukocytes, and spleen.