免疫原
The antiserum was produced against synthesized peptide derived from human SFRS11. AA range:211-260
特异性
SFRS11 Polyclonal Antibody detects endogenous levels of SFRS11 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010],
功能
function:May function in pre-mRNA splicing.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Colocalizes with spliceosome components.,subunit:Interacts with PUF60.,
蛋白名称
Serine/arginine-rich splicing factor 11
其他名称
SRSF11; SFRS11; Serine/arginine-rich splicing factor 11; Arginine-rich 54 kDa nuclear protein; p54; Splicing factor; arginine/serine-rich 11
细胞定位
Nucleus. Colocalizes with spliceosome components.
组织表达
Colon endothel,Epithelium,Fetal brain,Hepatoma,Human fetal