免疫原
Synthesized peptide derived from human FNIP2 AA range: 745-795
特异性
This antibody detects endogenous levels of human FNIP2
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
基因名称(Gene Name)
FNIP2 FNIPL KIAA1450 MAPO1
蛋白名称
Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)
Fields
>>mTOR signaling pathway
细胞定位
Lysosome membrane . Cytoplasm . Colocalizes with FLCN in the cytoplasm. .
组织表达
Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas (PubMed:18403135, PubMed:18663353, PubMed:27353360). Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue (PubMed:18403135). Higher levels detected in oncocytoma tumors than in normal kidney. Higher levels detected in renal cell carcinoma tumors than in normal kidney tissue (PubMed:27353360).