免疫原
Synthesized peptide derived from human SIA7B AA range: 219-269
特异性
This antibody detects endogenous levels of SIA7B at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008],
功能
catalytic activity:CMP-N-acetylneuraminate + glycano-beta-D-galactosyl-1,3-(N-acetyl-D-galactosaminyl)-glycoprotein = CMP + glycano-beta-D-galactosyl-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.,online information:GlycoGene database,online information:ST6GalNAc II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.,
基因名称(Gene Name)
ST6GALNAC2 SIAT7B SIATL1 STHM
Fields
>>Mucin type O-glycan biosynthesis;>>Metabolic pathways
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
组织表达
Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.