免疫原
Synthesized peptide derived from human SG1D1 AA range: 18-68
特异性
This antibody detects endogenous levels of SG1D1 at Human
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008],
功能
function:May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.,mass spectrometry: PubMed:9720917,similarity:Belongs to the secretoglobin family. Lipophilin subfamily.,subunit:Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head.,tissue specificity:Expressed in lachrymal gland, thymus, kidney, testis, ovary and salivary gland.,
基因名称(Gene Name)
SCGB1D1 LIPHA
组织表达
Expressed in lachrymal gland, thymus, kidney, testis, ovary and salivary gland.