免疫原
Synthesized peptide derived from human INCA1 AA range: 10-60
特异性
This antibody detects endogenous levels of INCA1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
PTM:Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues.,similarity:Belongs to the INCA family.,subunit:Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2.,tissue specificity:Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors.,
基因名称(Gene Name)
INCA1 HSD45
细胞定位
Nucleus . Cytoplasm .
组织表达
Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors (PubMed:15159402). Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells (PubMed:21540187).