免疫原
Synthesized peptide derived from human KCNT2 AA range: 689-739
特异性
This antibody detects endogenous levels of KCNT2 at Human/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,
基因名称(Gene Name)
KCNT2 SLICK
细胞定位
Cell membrane ; Multi-pass membrane protein .