免疫原
Synthesized peptide derived from human RBBP9 AA range: 108-158
特异性
This antibody detects endogenous levels of RBBP9 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. [provided by RefSeq, Jul 2008],
功能
function:May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.,similarity:Belongs to the RBBP9 family.,tissue specificity:Widely expressed. Expressed at higher levels in tumor tissues than in normal tissues.,
基因名称(Gene Name)
RBBP9 BOG RBBP10
细胞定位
nucleus,nucleolus,cytoplasm,extracellular exosome,
组织表达
Expressed at higher levels in tumor tissues such as carcinoma.