免疫原
Synthesized peptide derived from human LCE2B AA range: 31-81
特异性
This antibody detects endogenous levels of LCE2B at Human
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008],
功能
function:Precursors of the cornified envelope of the stratum corneum.,induction:By calcium and UVB.,miscellaneous:Belongs to the LCE cluster present on 1q21.,similarity:Belongs to the LCE family.,tissue specificity:Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.,
基因名称(Gene Name)
LCE2B LEP10 SPRL1B XP5
细胞定位
cornified envelope,cytoplasm,
组织表达
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.