免疫原
Synthesized peptide derived from human PARVA AA range: 178-228
特异性
This antibody detects endogenous levels of PARVA at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010],
功能
function:Probably plays a role in the regulation of cell adhesion and cytoskeleton organization.,similarity:Belongs to the parvin family.,similarity:Contains 2 CH (calponin-homology) domains.,subcellular location:Constituent of focal adhesions.,subunit:Interacts with TGFB1I1 (By similarity). Interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. Interacts with CDGAP.,tissue specificity:Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.,
基因名称（Gene Name）
PARVA MXRA2
细胞定位
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line . Constituent of focal adhesions. Associates with the actin cytoskeleton.
组织表达
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.
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