免疫原
Synthesized peptide derived from human UPP2 AA range: 164-214
特异性
This antibody detects endogenous levels of UPP2 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,function:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.,similarity:Belongs to the PNP/UDP phosphorylase family.,tissue specificity:Predominantly expressed in kidney.,
Fields
>>Pyrimidine metabolism;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Nucleotide metabolism
细胞定位
cytoplasm,cytosol,type III intermediate filament,
组织表达
Predominantly expressed in kidney.
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