免疫原
Synthesized peptide derived from human GOGA1 AA range: 169-219
特异性
This antibody detects endogenous levels of GOGA1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.320% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010],
功能
disease:Antibodies against GOLGA1 are present in sera from patients with Sjoegren syndrome. Sera from patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex.,domain:Extended rod-like protein with coiled-coil domains.,function:Probably involved in maintaining Golgi structure.,similarity:Contains 1 GRIP domain.,subunit:Binds RAB6A.,
其他名称
Golgin subfamily A member 1 (Golgin-97)
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein . Golgi apparatus, trans-Golgi network membrane . Cytoplasmic vesicle, secretory vesicle, acrosome .
组织表达
Brain,Cervix carcinoma,Testis,