免疫原
The antiserum was produced against synthesized peptide derived from human PEVR2. AA range:235-284
特异性
GPR172B Polyclonal Antibody detects endogenous levels of GPR172B protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013],
功能
function:Acts as receptor for porcine endogenous retrovirus subgroup A (PERV-A).,similarity:Belongs to the PERVR family.,tissue specificity:Detected in a wide variety of tissues. High expression in testis.,
蛋白名称
Solute carrier family 52 riboflavin transporter member 1
其他名称
SLC52A1; GPR172B; PAR2; RFT1; Solute carrier family 52; riboflavin transporter, member 1; Porcine endogenous retrovirus A receptor 2; PERV-A receptor 2; Protein GPR172B; Riboflavin transporter 1; hRFT1
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.