免疫原
Synthesized peptide derived from human ZER1 AA range: 388-438
特异性
This antibody detects endogenous levels of ZER1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.318% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012],
功能
function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.,
基因名称(Gene Name)
ZER1 C9orf60 ZYG ZYG11BL
其他名称
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)
细胞定位
Cul2-RING ubiquitin ligase complex,
组织表达
Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.