免疫原
Synthesized peptide derived from human S13A5 AA range: 313-363
特异性
This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.157% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],
功能
function:High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.,similarity:Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.,tissue specificity:Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.,
基因名称(Gene Name)
SLC13A5 NACT
其他名称
Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.