免疫原
Synthesized peptide derived from human REPI1 AA range: 10-60
特异性
This antibody detects endogenous levels of REPI1 at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.148% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.,similarity:Contains 15 C2H2-type zinc fingers.,subunit:Homodimers and homomultimers. Found in a complex with RIP60 and RIP100.,
基因名称(Gene Name)
REPIN1 RIP60 ZNF464
其他名称
Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464)
组织表达
Cervix carcinoma,Eye,Muscle,