免疫原
Synthesized peptide derived from human PGTA AA range: 312-362
特异性
This antibody detects endogenous levels of PGTA at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.,cofactor:Binds 1 zinc ion per dimer.,enzyme regulation:The enzymatic reaction requires the aid of a Rab escort protein (also called component A).,function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.,similarity:Belongs to the protein prenyltransferase subunit alpha family.,similarity:Contains 6 PFTA repeats.,subunit:Heterodimer of an alpha and a beta subunit, collectively called component B.,
其他名称
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
细胞定位
plasma membrane,Rab-protein geranylgeranyltransferase complex,
组织表达
Fetal brain,Lung,Thymus,Tongue,
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