免疫原
Synthesized peptide derived from human SYTL1 AA range: 333-383
特异性
This antibody detects endogenous levels of SYTL1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.101% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-triphosphate.,similarity:Contains 1 C2 domain.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,subcellular location:Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.,subunit:Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.,tissue specificity:Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea.,
基因名称(Gene Name)
SYTL1 SLP1 SB146
其他名称
Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1)
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.
组织表达
Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).