免疫原
Synthesized peptide derived from human DND1 AA range: 94-144
特异性
This antibody detects endogenous levels of DND1 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.33% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010],
功能
function:May play a role during primordial germ cell (PGC) development. However, does not seem to be essential for PGC migration.,similarity:Contains 2 RRM (RNA recognition motif) domains.,
基因名称(Gene Name)
DND1 RBMS4
其他名称
Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)
细胞定位
Nucleus . Cytoplasm . Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3 (By similarity). .