免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
GPR3 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012],
功能
function:Orphan receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye.,
基因名称(Gene Name)
GPR3 ACCA
蛋白名称
G-protein coupled receptor 3 (ACCA orphan receptor)
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.