免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
IGS11 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005],
功能
function:Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.,miscellaneous:The last 20 cytoplasmic amino-acids are not required for the cell adhesion function.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.,
基因名称(Gene Name)
IGSF11 BTIGSF CXADRL1 VSIG3
蛋白名称
Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3)
Fields
>>Cell adhesion molecules
细胞定位
Cell membrane ; Single-pass type I membrane protein .
组织表达
Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.