免疫原
Synthesized peptide derived from part region of human protein
特异性
TNR27 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016],
功能
function:Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Associates with TRAF1, TRAF3 and TRAF6.,
基因名称（Gene Name）
EDA2R TNFRSF27 XEDAR UNQ2448/PRO5727/PRO34080
蛋白名称
Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)
Fields
>>Cytokine-cytokine receptor interaction;>>NF-kappa B signaling pathway
细胞定位
Membrane; Single-pass type III membrane protein.
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