免疫原
Synthesized peptide derived from part region of human protein
特异性
RASM Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
功能
function:May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.,induction:By interleukin-9, but not by IL-2 or IL-4.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with RGL3.,tissue specificity:Expression highly restricted to the brain and heart.,
基因名称（Gene Name）
MRAS RRAS3
蛋白名称
Ras-related protein M-Ras (Ras-related protein R-Ras3)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Phospholipase D signaling pathway;>>Mitophagy - animal;>>Autophagy - animal;>>Cellular senescence;>>Apelin signaling pathway;>>C-type lectin receptor signaling pathway;>>Regulation of actin cytoskeleton;>>Proteoglycans in cancer
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
组织表达
Expression highly restricted to the brain and heart.
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