免疫原
Synthesized peptide derived from part region of human protein
特异性
THIOM Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008],
功能
function:Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Monomer.,tissue specificity:Widely expressed in adult (at protein level) and fetal tissues.,
基因名称(Gene Name)
TXN2 TRX2
蛋白名称
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Fields
>>NOD-like receptor signaling pathway;>>Parkinson disease;>>Salmonella infection;>>Fluid shear stress and atherosclerosis
组织表达
Widely expressed in adult (at protein level) and fetal tissues.